منابع مشابه
A serologic marker for fetal risk of congenital heart block.
OBJECTIVE To analyze the humoral immune response to Ro/SSA and La/SSB antigens in detail, in order to identify markers in mothers at high risk of having children with congenital heart block (CHB). METHODS Serum samples were obtained from 9 Ro/La-positive mothers who gave birth to affected children, from their 8 newborns with CHB, and from 26 Ro/La-positive mothers whose children were healthy....
متن کاملCorrelation of Maternal Autoantibodies with Fetal Congenital Heart Block.
BACKGROUND Autoimmune fetal congenital heart block (CHB) is the most severe manifestation of neonatal lupus, and it is seen when maternal autoimmune antibodies cross the placenta and damage the AV node of the fetus. CHB is mainly associated with maternal SLE with anti-Ro/SSA- and anti-La/SSB-positive status, and incidence of CHB increases when both the antibodies are present. This study was con...
متن کاملFetal Echo Doppler for Early Detection of Congenital Heart Block
Background: Fetal echo Doppler methods, detecting prolonged atrioventricular (AV) time intervals a mechanical PR interval corresponding to the electrical PR interval in ECG, have been proposed for surveillance of pregnancies at risk of complete congenital heart block (CCHB). The aim of this thesis was; to validate these Doppler methods by comparing AV time intervals from left ventricular inflow...
متن کاملFetal atrioventricular heart block.
As part of routine prenatal care, the obstetrician of a 25-year-old gravida 1, para 0 woman performed fetal heart-rate monitoring at 22 weeks gestational age. The fetal heart rate was 90 bpm, below the expected range of 120 –160 bpm. This finding prompted a subsequent fetal ultrasound and echocardiogram. The ultrasound exam showed no evidence of hydrops. Cardiac anatomy was normal, with 4 appro...
متن کاملFetal complete heart block.
In a series of over 6000 patients referred for fetal echocardiography during an eight year period, 37 fetuses were found to have complete heart block. There were 16 cases of isolated heart block and 21 cases associated with structural heart disease. All mothers of fetuses with isolated complete heart block had evidence of circulating syndrome Sjögren A antibody (Ro). Only one mother had clinica...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2001
ISSN: 0960-7692
DOI: 10.1046/j.1469-0705.2001.abs19-7.x